Browsing by Author "Neuparth, Teresa"
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- Assessing radiobiological effects of diagnostic level doses of ionizing radiation on zebrafish using comet assayPublication . Lemos, Joana; Costa, Pedro; Cunha, Lídia; Carvalho, António Paulo; Neuparth, Teresa; Genésio, Paula; Ponte, Fernanda; Costa, Paulo; Crespo, Paulo; Metello, Luís F.This paper relates with the application of zebrafish – Danio rerio – to the study of radiobiological effects of medical diagnostic level – low doses – of ionizing radiation. In recent years, the use of zebrafish has grown considerably, pointing more and more as a very interesting model in biomedical research, essentially because of the level of homology shared with the human genome, complemented by an easy and reasonably affordable practical side.
- The acute effect on three-dimensional cellular proliferation rate of low dose irradiation exposuresPublication . Costa, Pedro; Lemos, Joana; Cunha, Lídia; Neuparth, Teresa; Genésio, Paula; Ponte, Fernanda; Costa, Paulo; Crespo, Paulo; Metello, LuísLow doses of ionizing radiation are not yet consistently studied and documented. In such context, more advanced and complex biological models should be applied to obtain relevant data. Known limitations of monolayer cellular models and ever increasing difficulties to use some biological models, lead to develop advanced biological models, namely three-dimensional cell cultures.