Browsing by Author "Moreira, Paula I."
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- Associations between trace elements and cognitive decline: an exploratory 5-Year follow-up study of an elderly cohortPublication . Gerardo, Bianca; Pinto, Marina Cabral; Nogueira, Joana; Pinto, Paula; Almeida, Agostinho; Pinto, Edgar; Marinho-Reis, Paula; Diniz, Luísa; Moreira, Paula I.; Simões, Mário R.; Freitas, SandraTrace elements (TE) homeostasis is crucial in normal brain functioning. Although imbalances have the potential to exacerbate events leading neurodegenerative diseases, few studies have directly addressed the eventual relationships between TE levels in the human body and future cognitive status. The present study aimed to assess how different TE body-levels relate to cognitive decline..
- HUMMR Acts as a “roadblock” for mitochondrial transport in Alzheimer’s diseasePublication . Correia, Sónia C.; Pinho, Tiffany S.; Zhu, Xiongwei; Perry, George; Moreira, Paula I.Alterations in axonal transport of mitochondria play a critical role in Alzheimer’s disease (AD) neuropathology; however, the molecular mechanisms involved remain unexplored (Li et al., 2009).