Percorrer por autor "Dias, Alberto CP"
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- Screening of the activity of quercetin-biapigenin and their poly(ε-caprolactone)-loaded nanoparticles in HepG2 cellsPublication . Oliveira, Ana Isabel; Pinho, Cláudia; Sarmento, Bruno; Dias, Alberto CPHypericum perforatum extracts have been used for their antidepressive effects. A selected fraction (HP) containing quercetin and biapigenin proved to be neuroprotective. Liver is the organ primary responsible for compound metabolization and extremely susceptibility to toxic effects. This study aims to determine the hepatotoxic/protective activity of HP and HP PCL-loaded nanoparticles.