Publication
Polyethyleneiminomethyl phosphonic acid (PEI-MP) radiolabeled with technetium-99m as a potential new radiopharmaceutical for diagnosis of bladder cancer
| dc.contributor.author | Ferreira, Sara | |
| dc.contributor.author | Abrantes, Ana Margarida | |
| dc.contributor.author | Laranjo, Mafalda | |
| dc.contributor.author | Metello, Luís F. | |
| dc.contributor.author | Casalta-Lopes, João | |
| dc.contributor.author | Dormehl, Irene | |
| dc.contributor.author | Botelho, Maria Filomena | |
| dc.date.accessioned | 2015-07-09T15:57:31Z | |
| dc.date.available | 2015-07-09T15:57:31Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | Introduction: The polymer PEI-MP (polyethyleneiminomethyl phosphonic acid) might be labelled with 99mTc. It was initially synthesized for palliative therapy of bone metastases after convenient radiolabelling, however in biodistribution studies performed with different PEI-MP/radionuclides, was obvious that the bladder wall was a target organ [1-3], demonstrating a certain selectivity to bladder cells, and so, to bladder cancer cells. The aim of this study was to evaluate the efficacy of 99mTc-PEI-MP for diagnosis of bladder carcinoma, evaluating in vitro and in vivo the biokinetics and biodistribution of 99mTc-PEI-MP | en |
| dc.identifier.uri | http://hdl.handle.net/10400.22/6429 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | no | por |
| dc.title | Polyethyleneiminomethyl phosphonic acid (PEI-MP) radiolabeled with technetium-99m as a potential new radiopharmaceutical for diagnosis of bladder cancer | por |
| dc.type | other | |
| dspace.entity.type | Publication | |
| oaire.citation.title | International Symposium in Applied Bioimaging - Bioimaging 2014 | por |
| rcaap.rights | openAccess | por |
| rcaap.type | other | por |