REPOSITÓRIO P.PORTO

Scientific Repository of the Porto Polytechnic

The Scientific Repository of the Polytechnic Institute of Porto's main goal is to provide all the scientific production of teachers, researchers and students of the Polytechnic Institute of Porto when possible in full text.The mission of the Scientific Repository of the Polytechnic Institute of Porto comprises up between two factors of extreme importance, the availability of scientific information and the preservation of digital information."Key Market": to make available in free access all the scientific production of the Polytechnic Institute of Porto."Contribution": aid students, researchers, teachers and the general public in obtaining reliable scientific production."Distinction": commitment that each user meets their scientific needs.

Email recipp@sc.ipp.pt

Recent Submissions

A retrospective study in tumour characteristics and clinical outcomes of overweight and obese women with breast cancer

Publication . Luís, Carla; Dias, João; Firmino‑Machado, João; Fernandes, Rute; Pereira, Deolinda; Baylina, Pilar; Fernandes, Rúben; Soares, Raquel; BAYLINA MACHADO, PILAR

Obesity and breast cancer are two major pathologies closely associated with increasing incidence and mortality rates, especially amongst women. The association between both diseases have been thoroughly discussed but much is still to uncover. The aim of this study is to analyse tumour characteristics and clinical outcomes of overweight and obese women to disclosure potential associations and better understand the impact of obesity in breast cancer. Clinicopathological information of 2246 women were extracted from the institutional database of comprehensive cancer centre in Portugal diagnosed between 2012 and 2016. Women were stratifed according to body mass index as normal, overweight, and obese. Patients’ demographic information and tumour features (age, family history, topographic localization, laterality, histological type, and receptor status) were taken as independent variables and overall survival, tumour stage, diferentiation grade and bilaterality were considered clinical outcomes. The main results reveal that overweight and obesity are predominantly associated with worse outcomes in breast cancer patients. Obese patients present larger (p-value: 0.002; OR 1.422; 95% CI 1.134–1.783) and more poorly diferentiated tumours (p-value: 0.002; OR 1.480; 95% CI 1.154–1.898) and tend to have lower overall survival although without statistical signifcance (p-value: 0.117; OR 1.309; 95% CI 0.934–1.833). Overweighted women are more likely to have bilateral breast cancer (p-value: 0.017; OR 3.076; 95% CI 1.225–7.722) than obese women. The results also reveal that overweight women present less distant metastasis (p-value: 0.024; OR 0.525; 95%CI 0.299–0.920). Topographic localization and laterality did not achieve statistical signifcance.

2023Research article

Open access

Complexity Metrics for ClassSheet Models

Publication . Cunha, Jácome; Fernandes, João Paulo; Mendes, Jorge; Saraiva, João

2013

Open access

Querying Model-Driven Spreadsheets

Publication . Cunha, Jácome; Fernandes, João Paulo; Mendes, Jorge; Rui Pereira; Saraiva, João

2013

Open access

QuerySheet: A Bidirectional Query Environment for Model-Driven Spreadsheets

Publication . Orlando Belo; Cunha, Jácome; Fernandes, João Paulo; Mendes, Jorge; Rui Pereira; Saraiva, João

2013

Open access

A bidirectional model-driven spreadsheet environment

Publication . Cunha, Jácome; Mendes, Jorge; Fernandes, João Paulo; Saraiva, João

2012

Open access