Teixeira, DulceFerraz, RicardoPrudêncio, CristinaVieira, Mónica2023-11-232023-11-232022-01Teixeira, D., Ferraz, R., Prudêncio, C., & Vieira, M. (2022). Desenvolvimento, avaliação e quantificação de biomoléculas. Atas Do I Encontro de Investigação Da Escola Superior de Saúde Do Politécnico Do Porto, 149–153. https://doi.org/10.26537/recipp-22960978-989-9045-31-6 e.ISBN 978-989-9045-30-9http://hdl.handle.net/10400.22/23960The synthesis of new biomolecules, the evaluation of their potential biological activity or therapeutic application, as well as the monitoring of intervening biomolecules in pathological contexts is of great interest to the scientific, medical and pharmaceutical community. In the validation of synthesis, extraction and biological interaction methods, chromatographic methods play a fundamental role in the identification and quantification of these biomolecules of interest, whether these are potential new drugs, biomarkers or environmental indicators. In order to contribute to the identification and quantification of biomolecules with potential (bio) technological application, new chromatographic methodologies have been developed, namely based on liquid chromatography, using HPLC-DAD. In the development of new biomolecules, the bioactivity of compounds with potential application has been studied, such as Quinoxaline derivatives. In addition to the antimicrobiological action, the effect of this family of compounds in the modeling of oxidative stress in pathological context has been evaluated.engconference object10.26537/recipp-22960