An in vivo study to analyse the potential of 188Re-PEI-MP for metabolic radiotherapy of osteosarcoma and bladder carcinoma

Ferreira, SaraLaranjo, MafaldaBrito, AnaAbrantes, Ana MargaridaMetello, Luís F.Zeevart, JanLouw, WernerDormehl, IreneBotelho, Maria Filomena2015-07-092015-07-092011http://hdl.handle.net/10400.22/6469Introduction: 188Re is a promising radionuclide for metabolic therapy because of the emission of high energy beta-particles. The development of water-soluble polymers such as PEI-MP (polyethyleneimine, functionalised with methylphosphonate groups) that might be labeled with 188Re are recent approaches, with a strong potential for metabolic radiotherapy.engAn in vivo study to analyse the potential of 188Re-PEI-MP for metabolic radiotherapy of osteosarcoma and bladder carcinomaother