Pereira, A.I.Martins, E.C.Lopes, Manuel2022-01-142022-01-142020Pereira, A. I., Martins, E. C., & Lopes, M. P. (2020). Taguchi method application in the pilot production phase-a case study. Procedia Manufacturing, 51, 1069-1075. DOI 10.1016/j.promfg.2020.10.150http://hdl.handle.net/10400.22/1952230th International Conference on Flexible Automation and Intelligent Manufacturing (FAIM2021) -15-18 June 2021, Athens, GreeceThis work comes at the product and process development stage in a medical device company, namely the bone substitute. The production of bone substitutes has high regulatory requirements, also the consumer of these products has high-quality requirements. In the pilot production phase, a quality problem was detected in the bone substitute blocks. The work presented was developed in a real context requiring an understanding of the production process and the product. Through a multidisciplinary analysis allowed to direct the problem to the impregnation process. The study of the impregnation process was developed according to the DOE through the Taguchi method. For the experiment, six factors and one interaction allocated in an L8 array were identified. Results obtained show that the process variability is clearly superior to the effect of the studied factors. For future work, the removal of non-significant factors is recommended, adding new factors not included in the study.engDesign of Experiments (DOE)Taguchi MethodPilot Production PhaseMedical Devicesconference object10.1016/j.promfg.2020.10.150