Santos, MarleneCarvalho, S.Lima, L.Mota-Pereira, J.Pimentel, P.Maia, D.Correia, D.Gomes, S.Cruz, AgostinhoMedeiros, R.2022-11-292022-11-292015-03Santos, M., Carvalho, S., Lima, L., Mota-Pereira, J., Pimentel, P., Maia, D., Correia, D., Gomes, S., Cruz, A., & Medeiros, R. (2015, março). Influence of Il-18 genetic polymorphisms in antidepressant treatment phenotypes [Comunicação poster]. 23rd European Congress of Psychiatry.http://hdl.handle.net/10400.22/21120Recent studies suggested that immune activation and cytokines might be involved in depression. The proinflammatory cytokine interleukin-18 (IL-18) is less reported in depression but is still relevant since it is expressed in the brain and serum levels of IL-18 have been found to be increased in patients with moderate to severe depression. Therefore, it seems reasonable that IL-18 promoter SNPs may have an effect in antidepressant response phenotypes.engconference object10.1016/S0924-9338(15)30575-7