Morais, SimoneRyckaert, Christine P. M. C. A.Delerue-Matos, Cristina2013-11-262013-11-2620030003-27191532-236Xhttp://hdl.handle.net/10400.22/2955An adsorptive stripping voltammetric procedure for the determination of the antidepressant venlafaxine in urine using a mercury film microelectrode wasdeveloped. The method is based on controlled adsorptive accumulation of the drug at the potential of 1.00V (vs. Ag/AgCl) in the presence of 1.25 x10 -2 molL- 1 borate buffer (pH 8.7). Urine samples were analyzed directly after performing a ten-fold dilution with the supporting electrolyte but without other pretreatment. The limit of detection obtained for a 30 s collection time was 0.693x 10- 6 mol L -1. Recovery experimentsgave good results at the 10 -6 mol L- 1 level (bias less 5% were obtained).engVenlafaxineMercury film microelectrodeAdsorptive stripping voltammetryUrinejournal article10.1081/AL-120024339