Silva, LilianaCoelho, PedroSoares, RaquelPrudêncio, CristinaVieira, Mónica2024-06-142024-06-142018-05-18Silva, L., Coelho, P., Soares, R., Prudêncio, C., & Vieira, M. (2018). Evaluation of quinoxaline-1,4-dioxide and derivatives biological activity in normal and tumour cell. Book of abstracts of the III Encontro de Biotecnologia Medicinal/ I Iberian Congress on Medicinal Biotechnology, 24. https://paginas.ess.ipp.pt/ebtm/2018/3EBtM_BookOfAbstracts.pdf978-989-20-8533-3http://hdl.handle.net/10400.22/25659Quinoxaline derivatives are synthetic heterocyclic compounds with multiples pharmacological applications and biological effects. Previous studies of our group about the biological activity in eukaryotic and prokaryotic microbial models with quinoxaline-1,4-dioxide (QNX) derivatives concluded a selective antimicrobial activity in gram negative strains. To further evaluate these compounds’ potential, we investigated the biologic activity in vitro of this chemical structures in normal and tumour cells lines.engQuinoxaline-14-dioxide and derivativesNormal and tumour cellIC50Evaluation of quinoxaline-1,4-dioxide and derivatives biological activity in normal and tumour cellconference object