Cunha, LídiaDamiani, DaniraAlves, Cecília J.Metello, Luís F.Summavielle, Teresa2015-05-272015-05-272010-10-09http://hdl.handle.net/10400.22/6125Introduction: Acetyl-L-Carnitine (ALC) has been proposed to have beneficial effects in chronic neurodegenerative disorders caused by production of abnormal proteins, mitochondrial dysfunction and oxidative stress. Recently, our group demonstrated that pre-treatment with ALC confers effective neuroprotection against 3,4- methylenedioximethamphetamine (MDMA)-induced neurotoxicity. These pre-clinical studies reinforce the beneficial potential of ALC as a neuroprotectant in neurodegenerative disorders. However, little is known about the molecular mechanisms underlying ALC action.engStudy of Mechanisms for Acetyl-L-Carnitine Neuroprotective Actionlecture