Radiolabeled polyethyleneiminomethyl phosphonic acid as a molecule with potential for diagnosis and therapy. Comparative study on models of bladder cancer and osteossarcoma.

Ferreira, SaraAbrantes, Ana MargaridaBrito, AnaLaranjo, MafaldaMetello, Luís F.Zeevart, JanLouw, WernerDormehl, IreneBotelho, Maria Filomena2015-07-092015-07-092013http://hdl.handle.net/10400.22/6458Introduction: The polymer PEI-MP (polyethyleneiminomethyl phosphonic acid) that might be labeled with 99mTc and 188Re, have a strong potential for diagnosis and metabolic radiotherapy, respectively. The aim of this study was to evaluate the efficacy of 99mTc-PEI-MP for diagnosis and 188Re-PEI-MP as therapeutic agent, in a comparative study using in vitro and in vivo models of bladder cancer and osteossarcomaengRadiolabeled polyethyleneiminomethyl phosphonic acid as a molecule with potential for diagnosis and therapy. Comparative study on models of bladder cancer and osteossarcoma.other