Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.22/7484
Título: Plant derived and dietary phenolic antioxidants: Anticancer properties
Autor: Roleira, Fernanda M.F.
Tavares-da-Silva, Elisiário J.
Varela, Carla L.
Costa, Saul C.
Silva, Tiago
Garrido, Jorge
Borges, Fernanda
Palavras-chave: Dietary phenolic antioxidants
Synthetic phenolic antioxidants
Cancer
Data: Set-2015
Editora: Elsevier
Relatório da Série N.º: Food Chemistry;183
Resumo: n this paper, a review of the literature on the phenolic compounds with anticancer activity published between 2008 and 2012 is presented. In this overview only phenolic antioxidant compounds that display significant anticancer activity have been described. In the first part of this review, the oxidative and nitrosative stress relation with cancer are described. In the second part, the plant-derived food extracts, containing identified phenolic antioxidants, the phenolic antioxidants isolated from plants and plant-derived food or commercially available and the synthetic ones, along with the type of cancer and cells where they exert anticancer activity, are described and summarized in tables. The principal mechanisms for their anti-proliferative effects were also described. Finally, a critical analysis of the studies and directions for future research are included in the conclusion.
URI: http://hdl.handle.net/10400.22/7484
DOI: 10.1016/j.foodchem.2015.03.039
Versão do Editor: http://www.sciencedirect.com/science/article/pii/S0308814615004021
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