Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.22/6764
Título: Biomimetic norfloxacin sensors made of molecularly-imprinted materials for potentiometric transduction
Autor: Moreira, Felismina T. C.
Freitas, Victor De
Sales, M. Goreti F.
Palavras-chave: Norfloxacin
Molecularly-imprinted sensors
Data: 2011
Editora: Springer
Resumo: A biomimetic sensor for norfloxacin is presented that is based on host-guest interactions and potentiometric transduction. The artificial host was imprinted into polymers made from methacrylic acid and/or 2-vinyl pyridine. The resulting particles were entrapped in a plasticized poly(vinyl chloride) (PVC) matrix. The sensors exhibit near-Nernstian response in steady state evaluations, and detection limits range from 0.40 to 1.0 μg mL−1, respectively, and are independent of pH values at between 2 and 6, and 8 and 11, respectively. Good selectivity was observed over several potential interferents. In flowing media, the sensors exhibit fast response, a sensitivity of 68.2 mV per decade, a linear range from 79 μM to 2.5 mM, a detection limit of 20 μg mL−1, and a stable baseline. The sensors were successfully applied to field monitoring of norfloxacin in fish samples, biological samples, and pharmaceutical products.
URI: http://hdl.handle.net/10400.22/6764
DOI: 10.1007/s00604-010-0464-4
Versão do Editor: http://link.springer.com/article/10.1007%2Fs00604-010-0464-4
Aparece nas colecções:ISEP – BioMark – Artigos

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