Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.22/6762
Título: Biomimetic sensors of molecularly-imprinted polymers for chlorpromazine determination
Autor: Moreira, Felismina T. C.
Sales, M. Goreti F.
Palavras-chave: Chlorpromazine
Molecularly-imprinted sensors
Potentiometry
FIA
Fish
Data: 2011
Editora: Elsevier
Resumo: A new man-tailored biomimetic sensor for Chlorpromazine host-guest interactions and potentiometric transduction is presented. The artificial host was imprinted within methacrylic acid, 2-vinyl pyridine and 2-acrylamido-2-methyl-1-propanesulfonic acid based polymers. Molecularly imprinted particles were dispersed in 2-nitrophenyloctyl ether and entrapped in a poly(vinyl chloride) matrix. Slopes and detection limits ranged 51–67 mV/decade and 0.46–3.9 μg/mL, respectively, in steady state conditions. Sensors were independent from the pH of test solutions within 2.0–5.5. Good selectivity was observed towards oxytetracycline, doxytetracycline, ciprofloxacin, enrofloxacin, nalidixic acid, sulfadiazine, trimethoprim, glycine, hydroxylamine, cysteine and creatinine. Analytical features in flowing media were evaluated on a double-channel manifold, with a carrier solution of 5.0 × 10−2 mol/L phosphate buffer. Near-Nernstian response was observed over the concentration range 1.0 × 10−4 to 1.0 × 10−2 mol/L. Average slopes were about 48 mV/decade. The sensors were successfully applied to field monitoring of CPZ in fish samples, offering the advantages of simplicity, accuracy, automation feasibility and applicability to complex samples.
URI: http://hdl.handle.net/10400.22/6762
DOI: 10.1016/j.msec.2011.04.012
Versão do Editor: http://www.sciencedirect.com/science/article/pii/S0928493111001172
Aparece nas colecções:ISEP – BioMark – Artigos

Ficheiros deste registo:
Ficheiro Descrição TamanhoFormato 
ART_FelisminaMoreira3_2011.pdf742,39 kBAdobe PDFVer/Abrir    Acesso Restrito. Solicitar cópia ao autor!


FacebookTwitterDeliciousLinkedInDiggGoogle BookmarksMySpace
Formato BibTex MendeleyEndnote Degois 

Todos os registos no repositório estão protegidos por leis de copyright, com todos os direitos reservados.