Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.22/6701
Título: Chitosan/AuNPs Modified Graphene Electrochemical Sensor for Label-Free Human Chorionic Gonadotropin Detection
Autor: Teixeira, Sofia
Ferreira, Nádia S.
Conlan, Robert S.
Guy, O. J.
Sales, M. Goreti F.
Palavras-chave: Immunosensor
Screen-printed electrode
Graphene
Antibody
Chitosan
Human chorionic gonadotropin
Data: 2014
Editora: Wiley
Resumo: A new immunosensor is presented for human chorionic gonadotropin (hCG), made by electrodepositing chitosan/gold-nanoparticles over graphene screen-printed electrode (SPE). The antibody was covalently bound to CS via its Fc-terminal. The assembly was controlled by electrochemical Impedance Spectroscopy (EIS) and followed by Fourier Transformed Infrared (FTIR). The hCG-immunosensor displayed linear response against the logarithm-hCG concentration for 0.1–25 ng/mL with limit of detection of 0.016 ng/mL. High selectivity was observed in blank urine and successful detection of hCG was also achieved in spiked samples of real urine from pregnant woman. The immunosensor showed good detection capability, simplicity of fabrication, low-cost, high sensitivity and selectivity.
URI: http://hdl.handle.net/10400.22/6701
DOI: 10.1002/elan.201400311
Versão do Editor: http://onlinelibrary.wiley.com/doi/10.1002/elan.201400311/full
Aparece nas colecções:ISEP – BioMark – Artigos

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