Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.22/6276
Título: Picocyanobacteria From a Clade Of Marine Cyanobium Revealed Bioactive Potential Against Microalgae, Bacteria, And Marine
Autor: Costa, Maria Sofia
Costa, Margarida
Ramos, Vitor
Leão, Pedro N.
Barreiro, Aldo
Vasconcelos, Vítor
Martins, Rosário
Data: 2015
Editora: Taylor & Francis
Resumo: The production of bioactive compounds either toxic or with pharmacological applications by cyanobacteria is well established. However, picoplanktonic forms within this group of organisms have rarely been studied in this context. In this study, the toxicological potential of picocyanobacteria from a clade of marine Cyanobium strains isolated from the Portuguese coast was examined using different biological models. First, strains were identified by applying morphological and molecular approaches and cultured under lab conditions. A crude extract and three fractions reflecting a preliminary segregation of lipophilic metabolites were tested for toxicity with the marine microalga Nannochloropsis sp., the bacteria Pseudomonas sp., the brine shrimp Artemia salina, and fertilized eggs of the sea urchin Paracentrotus lividus. No significant apparent adverse effects were noted against Artemia salina. However, significant adverse effects were found in all other assays, with an inhibition of Nannochloropsis sp. and Pseudomonas sp. growth and marked reduction in Paracentrotus lividus larvae length. The results obtained indicated that Cyanobium genus may serve as a potential source of interesting bioactive compounds and emphasize the importance of also studying smaller picoplanktonic fractions of marine cyanobacteria.
Peer review: yes
URI: http://hdl.handle.net/10400.22/6276
DOI: 10.1080/15287394.2014.991466
Versão do Editor: http://www.tandfonline.com/doi/pdf/10.1080/15287394.2014.991466
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