Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.22/5622
Título: Auditory event-related potentials in children with benign epilepsy with centro-temporal spikes
Autor: Tomé, David
Sampaio, Mafalda
Mendes-Ribeiro, José
Barbosa, Fernando
Marques-Teixeira, João
Palavras-chave: Benign rolandic epilepsy
N1
N2b
auditory processing
MMN
Data: 2014
Editora: Elsevier
Relatório da Série N.º: 10;
Resumo: Benign focal epilepsy in childhood with centro-temporal spikes (BECTS) is one of the most common forms of idiopathic epilepsy, with onset from age 3 to 14 years. Although the prognosis for children with BECTS is excellent, some studies have revealed neuropsychological deficits in many domains, including language. Auditory event-related potentials (AERPs) reflect activation of different neuronal populations and are suggested to contribute to the evaluation of auditory discrimination (N1), attention allocation and phonological categorization (N2), and echoic memory (mismatch negativity – MMN). The scarce existing literature about this theme motivated the present study, which aims to investigate and document the existing AERP changes in a group of children with BECTS. AERPs were recorded, during the day, to pure and vocal tones and in a conventional auditory oddball paradigm in five children with BECTS (aged 8–12; mean = 10 years; male = 5) and in six gender and age-matched controls. Results revealed high amplitude of AERPs for the group of children with BECTS with a slight latency delay more pronounced in fronto-central electrodes. Children with BECTS may have abnormal central auditory processing, reflected by electrophysiological measures such as AERPs. In advance, AERPs seem a good tool to detect and reliably reveal cortical excitability in children with typical BECTS.
Peer review: yes
URI: http://hdl.handle.net/10400.22/5622
DOI: doi:http://dx.doi.org/10.1016/j.eplepsyres.2014.09.021
Versão do Editor: doi:http://dx.doi.org/10.1016/j.eplepsyres.2014.09.021
Aparece nas colecções:ESTSP - CEMAH - Artigos
ESTSP - AUD - Artigos

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