Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.22/3527
Título: Hydroxycinnamic acid antioxidants: an electrochemical overview
Autor: Teixeira, José
Gaspar, Alexandra
Garrido, E. Manuela
Garrido, Jorge
Borges, Fernanda
Palavras-chave: Hydroxycinnamic acid
Antioxidants
Electrochemistry
Data: 2013
Editora: Hindawi Publishing Corporation
Relatório da Série N.º: BioMed Research International; Vol. 2013
Resumo: Hydroxycinnamic acids (such as ferulic, caffeic, sinapic, and p-coumaric acids) are a group of compounds highly abundant in food that may account for about one-third of the phenolic compounds in our diet. Hydroxycinnamic acids have gained an increasing interest in health because they are known to be potent antioxidants. These compounds have been described as chain-breaking antioxidants acting through radical scavenging activity, that is related to their hydrogen or electron donating capacity and to the ability to delocalize/stabilize the resulting phenoxyl radical within their structure.The free radical scavenger ability of antioxidants can be predicted from standard one-electron potentials. Thus, voltammetric methods have often been applied to characterize a diversity of natural and synthetic antioxidants essentially to get an insight into their mechanism and also as an important tool for the rational design of new and potent antioxidants.The structure-property-activity relationships (SPARs) correlations already established for this type of compounds suggest that redox potentials could be considered a good measure of antioxidant activity and an accurate guideline on the drug discovery and development process. Due to its magnitude in the antioxidant field, the electrochemistry of hydroxycinnamic acid-based antioxidants is reviewed highlighting the structure-property-activity relationships (SPARs) obtained so far.
Peer review: yes
URI: http://hdl.handle.net/10400.22/3527
ISSN: 2314-6141
Versão do Editor: http://www.hindawi.com/journals/bmri/2013/251754/
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